Immunovant Reports Results of Batoclimab in P-II Trial for the Treatment of Graves’ Disease
Shots:
- The P-II trial evaluates the safety & efficacy of batoclimab in patients with Graves’ Disease who are hyperthyroid despite treatment with an anti-thyroid medication (ATD). The enrolled patients initially received 680mg (SC, qw) of batoclimab for 12wks. followed by 340mg (SC, qw) for 12wks.
- As per the results, IgG reduction in patients receiving 680mg dosage was up to 87% with a mean reduction of 81% after 12wks. whereas reduction with 340mg was lower. Moreover, deeper reductions were observed in anti-TSHR autoantibodies with 680mg of batoclimab vs 340mg
- Additionally, in clinical parameters, incl. the percentage of patients whose ATD dose was reduced & whose ATD was discontinued, higher responses were observed with 680mg vs 340mg
Ref: Immunovant | Image: Immunovant
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Kritika is a content writer at PharmaShots. She is interested in covering recent innovations from the pharma & MedTech industry. She covers news related to Product approvals, clinical trial results, and updates. She can be contacted at connect@pharmashots.com.